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1.

Author Correction: STEEP mediates STING ER exit and activation of signaling.

Zhang, Bao-Cun; Nandakumar, Ramya; Reinert, Line S; Huang, Jinrong; Laustsen, Anders; Gao, Zong-Liang; Sun, Cheng-Long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong-Gang; Stenmark, Harald; Doucet, Christine M; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J; Enghild, Jan J; Bak, Rasmus O; Thomsen, Martin K; Paludan, Søren R.

Nat Immunol; 21(11): 1468-1469, 2020 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-32929276

2.

STEEP mediates STING ER exit and activation of signaling.

Zhang, Bao-Cun; Nandakumar, Ramya; Reinert, Line S; Huang, Jinrong; Laustsen, Anders; Gao, Zong-Liang; Sun, Cheng-Long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong-Gang; Stenmark, Harald; Doucet, Christine M; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J; Enghild, Jan J; Bak, Rasmus O; Thomsen, Martin K; Paludan, Søren R.

Nat Immunol; 21(8): 868-879, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32690950

3.

A universe of second messengers for cGLR-STING signaling.

Wei, Xubiao; Zhang, Conggang.

Immunity; 56(9): 1975-1977, 2023 09 12.

Artículo en Inglés | MEDLINE | ID: mdl-37703824

4.

SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.

Hou, Yanfei; Wang, Zhimeng; Liu, Peiyuan; Wei, Xubiao; Zhang, Zhengyin; Fan, Shilong; Zhang, Lulu; Han, Fangping; Song, Yikang; Chu, Ling; Zhang, Conggang.

Immunity; 56(11): 2492-2507.e10, 2023 Nov 14.

Artículo en Inglés | MEDLINE | ID: mdl-37890481

5.

Navigating COVID-19: Starting a lab during the pandemic.

Ordovás-Montañés, José; Gerlach, Carmen; Moraes-Vieira, Pedro; Vento-Tormo, Roser; Zhang, Conggang; Jurado, Kellie Ann.

Immunity; 54(10): 2169-2171, 2021 10 12.

Artículo en Inglés | MEDLINE | ID: mdl-34644549

6.

Microtubule disruption synergizes with STING signaling to show potent and broad-spectrum antiviral activity.

Han, Jing; Wang, Zhimeng; Han, Fangping; Peng, Bo; Du, Juanjuan; Zhang, Conggang.

PLoS Pathog; 20(2): e1012048, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38408104

7.

Structural basis of STING binding with and phosphorylation by TBK1.

Zhang, Conggang; Shang, Guijun; Gui, Xiang; Zhang, Xuewu; Bai, Xiao-Chen; Chen, Zhijian J.

Nature; 567(7748): 394-398, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30842653

8.

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.

Shang, Guijun; Zhang, Conggang; Chen, Zhijian J; Bai, Xiao-Chen; Zhang, Xuewu.

Nature; 567(7748): 389-393, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30842659

9.

ORP9 and ORP10 form a heterocomplex to transfer phosphatidylinositol 4-phosphate at ER-TGN contact sites.

He, Ruyue; Liu, Furong; Wang, Hui; Huang, Shuai; Xu, Kai; Zhang, Conggang; Liu, Yinghui; Yu, Haijia.

Cell Mol Life Sci; 80(3): 77, 2023 Feb 28.

Artículo en Inglés | MEDLINE | ID: mdl-36853333

10.

USP15 promotes cGAS activation through deubiquitylation and liquid condensation.

Shi, Chengrui; Yang, Xikang; Hou, Yanfei; Jin, Xue; Guo, Lerui; Zhou, Yi; Zhang, Conggang; Yin, Hang.

Nucleic Acids Res; 50(19): 11093-11108, 2022 10 28.

Artículo en Inglés | MEDLINE | ID: mdl-36243958

11.

cGAS restricts colon cancer development by protecting intestinal barrier integrity.

Hu, Shuiqing; Fang, Yan; Chen, Xiang; Cheng, Tianlei; Zhao, Miaoqing; Du, Mingjian; Li, Tuo; Li, Minghao; Zeng, Zhiqun; Wei, Yonglong; Gu, Zhimin; Zhang, Conggang; Sun, Lijun; Chen, Zhijian J.

Proc Natl Acad Sci U S A; 118(23)2021 06 08.

Artículo en Inglés | MEDLINE | ID: mdl-34074794

12.

The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20.

Zhang, Conggang; Wang, Rongchun; Liu, Zeyu; Bunker, Eric; Lee, Schuyler; Giuntini, Michelle; Chapnick, Douglas; Liu, Xuedong.

J Biol Chem; 294(18): 7472-7487, 2019 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-30885942

13.

Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response.

Zhang, Conggang; Liu, Zeyu; Bunker, Eric; Ramirez, Adrian; Lee, Schuyler; Peng, Yinghua; Tan, Aik-Choon; Eckhardt, S Gail; Chapnick, Douglas A; Liu, Xuedong.

J Biol Chem; 292(36): 15105-15120, 2017 09 08.

Artículo en Inglés | MEDLINE | ID: mdl-28673964

14.

Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.

Lee, Schuyler; Zhang, Conggang; Liu, Xuedong.

J Biol Chem; 290(2): 904-17, 2015 Jan 09.

Artículo en Inglés | MEDLINE | ID: mdl-25404737

15.

Crystal structure of DszC from Rhodococcus sp. XP at 1.79 Å.

Liu, Shiheng; Zhang, Conggang; Su, Tiantian; Wei, Tiandi; Zhu, Deyu; Wang, Kang; Huang, Yan; Dong, Yuhui; Yin, Kun; Xu, Sujuan; Xu, Ping; Gu, Lichuan.

Proteins; 82(9): 1708-20, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-24470304

16.

Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response.

Li, Ning; Zhang, Conggang; Li, Bingqing; Liu, Xiuhua; Huang, Yan; Xu, Sujuan; Gu, Lichuan.

J Biol Chem; 287(12): 8912-9, 2012 Mar 16.

Artículo en Inglés | MEDLINE | ID: mdl-22291019

17.

NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking.

Zhang, Lulu; Wei, Xubiao; Wang, Zhimeng; Liu, Peiyuan; Hou, Yanfei; Xu, Yifang; Su, Huili; Koci, Matthew D; Yin, Hang; Zhang, Conggang.

Cell Rep; 42(3): 112185, 2023 03 28.

Artículo en Inglés | MEDLINE | ID: mdl-36857187

18.

Discovery of Podofilox as a Potent cGAMP-STING Signaling Enhancer with Antitumor Activity.

Han, Jing; Hu, Shuiqing; Hu, Yawei; Xu, Yifang; Hou, Yanfei; Yang, Yinlong; Su, Huili; Zhang, Zhengyin; Liu, Peng; Sun, Xuxu; Zhang, Conggang.

Cancer Immunol Res; 11(5): 583-599, 2023 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-36921097

19.

Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity.

Wang, Chaoyu; Zhang, Ruoshi; He, Jia; Yu, Lvshan; Li, Xinyan; Zhang, Junxia; Li, Sai; Zhang, Conggang; Kagan, Jonathan C; Karp, Jeffrey M; Kuai, Rui.

Nat Commun; 14(1): 3877, 2023 06 30.

Artículo en Inglés | MEDLINE | ID: mdl-37391428

20.

Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction.

Liu, Shiheng; Zhang, Conggang; Li, Ning; Niu, Bei; Liu, Mengyuan; Liu, Xiuhua; Wei, Tiandi; Zhu, Deyu; Huang, Yan; Xu, Sujuan; Gu, Lichuan.

Acta Crystallogr D Biol Crystallogr; 68(Pt 10): 1329-38, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22993087

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